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Table 2 Functional comparison of TMs constructed by ECIM and GRAM. Several key Gene Ontologies were implicated by both algorithms (bold text with matching numbers).

From: Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data

FDR adjusted p-value GO categories associated with ECIM modules GO categories associated with GRAM modules FDR adjusted p-value
2.7E-57 protein biosynthesis (1) oxidative phosphorylation 9.9E-12
2.1E-39 ribosome biogenesis and assembly amino acid metabolism (5) 2.9E-10
1.6E-17 meiosis protein biosynthesis (1) 4.7E-09
1.6E-16 spore wall assembly (sensu Fungi) (2) Sporulation (2) 3.7E-08
1.4E-15 sulfur metabolism (3) sulfur metabolism (3) 2.3E-07
1.2E-07 spore wall assembly (sensu Fungi) (2) protein biosynthesis (1) 3.3E-06
1.8E-07 DNA replication protein biosynthesis (1) 8.8E-06
2.7E-07 arginine biosynthesis Glycolysis 6.8E-05
5.7E-06 ribosome biogenesis protein biosynthesis (1) 1.3E-04
1.5E-03 mitosis (4) de novo' IMP biosynthesis 6.1E-04
2.4E-03 lagging strand elongation chromatin assembly or disassembly 1.6E-03
4.7E-03 amino acid biosynthesis (5) sulfur metabolism (3) 6.8E-03
1.0E-02 mitotic cell cycle (4) alcohol catabolism 7.3E-03
1.6E-02 cytokinesis, completion of separation interphase of mitotic cell cycle (4) 1.2E-02
3.6E-02 protein neddylation mitotic sister chromatid cohesion (4) 1.4E-02