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Figure 2 | BMC Bioinformatics

Figure 2

From: Predicting state transitions in the transcriptome and metabolome using a linear dynamical system model

Figure 2

Examples of the results of Bacillus data analyses. The horizontal axis shows the culture time in minutes. The vertical axis represents the cellular density values (blue plots) and the probabilistic index for transition (red plots). a) The results of analysis of the LB data (control culture condition). According to the probabilistic index, the first transition was predicted between time points 3 and 4, the period that corresponded to transition from exponential growth phase to the stationary phase as indicated by cellular density values. The probabilistic index identifies another state change between time points 6 and 7 during the "stationary" phase. b) The results of analysis of the MGM data (stress culture condition). According to the probabilistic index, a state change was predicted between time points 5 and 6, a period that corresponded to the transition from the exponential growth phase to the stationary phase. Compared to the results from cells grown in LB, the transition timing was different. This difference was caused by the lack of glucose in MGM.

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