Bridge-PLSR scores. The score plot for a two-component Bridge-PLSR model of the rat-liver data. Each array is represented by a spot coloured according to the administered drug-dose. The dashed lines indicate the location of design-points corresponding to different times of exposure. Two groups of high and low dosage can be seen along the first component, and the second component seems to model a time-effect. The two-component model accounts for 47% of the total variance in Y.