Figure 7
From: qPIPSA: Relating enzymatic kinetic parameters and interaction fields
Correlation between experimental ln(k cat /K m ) for bisphosphate and electrostatic potential differences for different aldolases (a) and prediction of k cat /K m for bisphosphate and class I aldolase (b). Correlations (a) are for differences in ln(kcat/Km) and electrostatic potential differences of each aldolase protein pair, after excluding ALF2_LAMJA and ALDOC_RAT. Predictions presented on part (b) were made for 8 aldolases based on ALDOB_RABIT and Q9U5N6_LEIME experimental parameters. Two outliers (with errors greater than 1.5 RMS deviation from y = x) are labeled, see text for discussion.