Figure 2From: A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficientConversion of measured concentrations to measured fluxes. First, the measured concentrations should be filtered. Then, fluxes are calculated from the concentration data (e.g. approximating the derivative or using a dynamic observer). Finally, the calculated fluxes may be filtered to get a smooth signal. Each step is conditioned by the operation mode (on-line or off-line).Back to article page