Table 1 Motifs significantly associated with gene expression changes in long lived mutants, sch9Δ, ras2Δ, and tor1Δ, with respect to the wild-type yeast.
|  |  | sch9Δ/wt | ras2Δ/wt | tor1Δ/wt | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
TF | Consensus | AC | p-value | q-value | AC | p-value | q-value | AC | p-value | q-value |
Fhl1 | RTGT-YGGRTG | 17.0 | 0 | 0 | 12.4 | 0 | 0 | 16.0 | 0 | 0 |
Msn2/4 | AGGGG | 15.0 | 0 | 0 | 15.4 | 0 | 0 | 12.5 | 0 | 0 |
Gis1 | AWAGGGAT | 12.0 | 0 | 0 | 12.5 | 0 | 0 | 10.6 | 0 | 0 |
Sum1/Ndt80 | GACACAAAA | 8.7 | 0 | 0 | 9.3 | 0 | 0 | 9.2 | 0 | 0 |
Pho4 | GY-TSKCACGTG-G | 7.3 | 0.0006 | 0.0013 | 9.5 | 0 | 0 | 8.7 | 0.0006 | 0.0025 |
Pdr3 | S-TCCGYGGAA | 6.0 | 0.011 | 0.012 | 9.1 | 0.0006 | 0.0009 | 4.4 | 0.067 | 0.077 |
Cad1 | ATTAGTAAGC | 5.9 | 0.014 | 0.015 | 8.5 | 0.0006 | 0.0009 | 4.6 | 0.033 | 0.048 |
Mig1 | CGCATMCCCCAC | 5.2 | 0.037 | 0.029 | 7.8 | 0 | 0 | 5.6 | 0.053 | 0.066 |
Met31 | MWGTGTGGCR | 4.9 | 0.041 | 0.031 | 9.2 | 0 | 0 | 5.4 | 0.047 | 0.061 |
Hsf1 | GAW-TTCTAGAA | 4.3 | 0.16 | 0.083 | 9.1 | 0 | 0 | 4.6 | 0.087 | 0.091 |
Zap1 | ACCYT-AGGTT | 3.8 | 0.43 | 0.16 | 12.1 | 0 | 0 | 5.2 | 0.045 | 0.059 |
Met4 | AMAA-TGTGG | 3.4 | 0.45 | 0.16 | 9.8 | 0 | 0 | 5.8 | 0.054 | 0.067 |
Cbf1 | RRTCACGTG | 3.3 | 0.45 | 0.16 | 9.2 | 0 | 0 | 5.3 | 0.038 | 0.054 |
Swi4 | CRCGAAAA | 3.2 | 0.39 | 0.15 | 3.5 | 0.27 | 0.080 | 11.8 | 0 | 0 |
Abf1 | CGT|-ARTGAT | -5.2 | 0.033 | 0.027 | -9.3 | 0 | 0 | -9.2 | 0 | 0 |
Xbp1 | GCCTCGARGMGR | -7.1 | 0 | 0 | 4.4 | 0.24 | 0.075 | -3.3 | 0.21 | 0.17 |