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Table 3 Validation of I-Ag7 experimental motifs

From: Predicting peptides binding to MHC class II molecules using multi-objective evolutionary algorithms

Experimental Motif

AUC value

 

Datasets

 

Reizis

Harrison

Gregori

Latek

Corper

MHCPEP

Yu

m(Reizis)

0.95

0.68

0.74

0.95

0.50

0.59

0.48

m(Harrison)

0.75

0.88

0.69

0.64

0.53

0.72

0.33

m(Gregori)

0.64

0.68

0.71

0.73

0.40

0.64

0.61

m(Latek)

0.66

0.72

0.80

0.95

0.64

0.52

0.75

m(Rammensee

0.49

0.64

0.76

0.82

0.60

0.48

0.43

m(Reich)

0.55

0.64

0.69

0.58

0.56

0.47

0.50

m(Amor)

0.69

0.54

0.66

0.70

0.56

0.66

0.40

  1. Performance measured by AUC of experimentally determined I-Ag7 motifs on their own datasets and other experimental datasets.