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Table 3 Details for PWM and SiteGA models of TFBS recognition

From: Effective transcription factor binding site prediction using a combination of optimization, a genetic algorithm and discriminant analysis to capture distant interactions

 

General parameters

Specific parameters

TF type

No. of training sequences

Window length, nt

PWM Type of matrix1

SiteGA Number of LPDs

E2F

40

38

DI

60

HNF4

29

17

DI

140

IRF1

28

33

DI

38

ISGF3

27

34

DI

36

NF-κB

43

30

DI

150

PPAR

37

25

DI

90

SF-1

53

30

DI

90

SREBP

37

18

MONO

110

STAT1

32

20

DI

150

  1. 1 – DI – dinucleotide PWM, MONO – mononucleotide PWM.