Skip to main content

Table 2 The ten compounds observed most commonly acting as regulators in E. coli, S. cerevisiae, H. sapiens and P. falciparum.

From: Regulation of metabolic networks by small molecule metabolites

  E. coli S. cerevisiae H. sapiens P. falciparum
Rank Compound Interactions Compound Interactions Compound Interactions Compound Interactions
1 ATP 70 ATP 65 ATP 51 ATP 56
2 ADP 70 ADP 52 Dithiothreitol 51 ADP 54
3 AMP 55 Orthophosphate 51 ADP 40 AMP 41
4 Orthophosphate 53 AMP 50 Orthophosphate 39 Orthophosphate 30
5 Mercaptoethanol 40 GTP 31 Mercaptoethanol 39 Pyrophosphate 29
6 Pyrophosphate 38 Pyrophosphate 31 AMP 31 GTP 28
7 GTP 35 Fe2+ 26 Glutathione 30 CTP 23
8 Fe2+ 35 NADH 25 Pyrophosphate 24 UTP 23
9 Glutathione 29 UTP 25 UTP 23 Adenosine 20
10 NADH 28 Glutathione 24 GTP 22 GDP 20