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Table 3 Comparison of those compounds that have different importance in regulation between E. coli and H. sapiens.

From: Regulation of metabolic networks by small molecule metabolites

   Rank Interactions
No. Compound E. coli H. sapiens E. coli H. sapiens
  More common in E. coli     
1 Pyruvate 10 26 25 4
2 Phosphoenolpyruvate 15 28 19 2
3 2-oxoglutarate 16 27 18 3
4 Pyridoxal phosphate 15 26 19 4
5 D-fructose 1,6-bisphosphate 14 25 20 5
6 ITP 18 28 15 2
7 Succinate 15 25 19 5
8 Oxaloacetate 20 28 13 2
9 L-alanine 21 28 12 2
10 L-serine 20 27 13 3
  More common in H. sapiens     
10 Nitric oxide 30 24 3 6
9 3'-5'-cyclic AMP 29 23 4 7
8 Phosphatidylethanolamine 28 22 5 8
7 UTP 12 7 22 23
6 Phosphatidate 30 23 3 7
5 Ethanol 25 18 8 12
4 1-acyl-glycero-3-phosphocholine 32 22 1 8
3 CDP 28 17 5 13
2 Phosphatidylserine 30 17 3 13
1 Phosphatidylcholine 28 13 5 17
  1. The number of interactions (EC numbers regulated) for each compound in the two organisms is shown in the right most columns. The compounds are then ranked in each organism by the number of interactions. The ranks for each compound in the two organism are shown in the middle columns. The ten compounds showing the largest decrease in rank (i.e. those that are more important in H. sapiens and the ten compounds showing the largest increase in rank (more important in E. coli are shown.