Figure 3

Translocation of a single DNA strand. (a) A crude molecular schematic illustrating a captured pseudo-aptamer before binding to the 5 nucleotide overhang complement. If the two strands were to separate, the strands would pass through the vestibule one strand at a time, as an aptamer melting event and ssDNA translocation. (b) Raw data shows the ssDNA translocation signals (most involving molecules that are already single-stranded upon capture).