Table 3 Genes involved in endothelial cells altered by riddelliine treatment in liver
Gene | Description | Locus link ID | Fold change | P-value |
|---|---|---|---|---|
* ADM | adrenomedullin | 25026 | 0.11 | 0.0010 |
EDG5 | endothelial differentiation, G-protein-coupled receptor, 5 | 29415 | 0.19 | 0.0000 |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 84050 | 0.25 | 0.0000 |
F11R | F11 receptor | 50848 | 0.43 | 0.0000 |
* F3 | coagulation factor III (thromboplastin, tissue factor) | 25584 | 0.36 | 0.0040 |
HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 24446 | 2.46 | 0.0080 |
* IL11 | interleukin 11 | 171040 | 2.38 | 0.0020 |
* IL8RA | interleukin 8 receptor, alpha | 54258 | 2.40 | 0.0020 |
* ITGA4 | integrin, alpha 4 | 311144 | 2.11 | 0.0020 |
* ITGA6 | integrin, alpha 6 | 114517 | 0.35 | 0.0000 |
LEPR | leptin receptor gene-related protein; leptin receptor | 16847 | 3.09 | 0.0032 |
* PRKCA | protein kinase C, alpha | 24680 | 2.41 | 0.0000 |
SLC7A5 | solute carrier family 7 member 5 | 50719 | 4.43 | 0.0040 |
* SRC | v-src sarcoma viral oncogene homolog (avian) | 83805 | 3.33 | 0.0050 |
* TNF | tumor necrosis factor (TNF superfamily, member 2) | 24835 | 0.05 | 0.0000 |
* TNFRSF6 | Fas (TNF receptor superfamily, member 6) | 246097 | 3.34 | 0.0010 |
* TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 246775 | 2.40 | 0.0020 |