Figure 1
From: ChIP-on-chip significance analysis reveals ubiquitous transcription factor binding
(Left) Magnitude versus amplitude (MA) plot of a ChIP-on-chip hybridization. The x-axis represents the average log2 intensity of the IP and WCE channels, and the y-axis represents the log2 ratio of IP/WCE. The black line represents the mean of the inferred null distribution, and the colored lines represent confidence intervals of .1, .01, and .001 probability. The model reveals an intensity dependent mean and variance of the null distribution, and a large number of probes are significantly enriched in the IP channel. (Right) The axes are the same as in the left panel, and colors represent the -log10 p-value of the null distribution.