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Table 1 Frequency of conn(k)-values resulting from randomly assigned U(k, l)-values

From: H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments

 

conn(k)

 

1

2

3

4

5

6

H2r_train (500 samples)

0.82

0.16

0.02

2.4·10-3

2.6·10-4

3.2·10-5

PF01053 (1000 samples)

0.90

0.10

4.2·10-3

1.3·10-4

-

-

  1. The datasets H2r_train, consisting of 20 randomly selected PFAM entries (see Additional file 1, Table S2) and PF01053 were analysed as explained. However, U(k, l)-values were assigned randomly. For H2r_train, 500 MSAs were analysed; for PF01053, 1000 experiments were done. For all experiments, the number of residues possessing the respective conn(k)-values was determined. The table lists frequency values deduced from the analysis of 75 HSRPs per sample.