Figure 5
From: Predicting cancer involvement of genes from heterogeneous data
The average number of cancer types in which genes appear differentially expressed (A) and the probability of being a cancer gene according to structural, functional and evolutionary properties (B) are plotted as a function the cancer linker degree (CLD) of the gene products. A) The average number of cancer types shown are for an accumulative CLD (i.e. CLD 5 represents proteins with CLD ≥ 5). The average protein in the dataset is represented by CLD 0. Known cancer genes appear differentially expressed in an average of 2.8 cancer types. B) The average SF-Probabilities shown are for an accumulative CLD (i.e. CLD 5 represents proteins with CLD ≥ 5). The average protein in the dataset is represented by CLD 0. Known cancer genes had an average SF-Probability of 0.41.