Figure 2
From: Improving protein function prediction methods with integrated literature data
Modified ROC curves for Functional Flow. Number of proteins predicted incorrectly (FP) versus number of proteins predicted correctly (TP). Abbreviations: GOMF – GO SLIM Molecular Function; GOBP – GO SLIM Biological Process; PPI ONLY – only edges from experiments measuring protein-protein interactions, such as yeast two-hybrid and affinity precipitation; GENETIC ONLY – only edges from genetic assays, such as synthetic lethality studies; PPI+GENETIC – edges from both PPI and from genetic assays, such as synthetic lethality studies; PPI+COLIT – edges from both PPI and edges between proteins found by literature co-occurrence, where Best and Worst correspond to the best and worst combinations of threshold setting and co-occurrence measure, respectively (c.f. Figure 5).