Figure 2
From: Conserved co-expression for candidate disease gene prioritization
Filtering out insignificant co-expression improves performance. When disease gene pairs with co-expression scores that do not differ significantly from those of randomized datasets are filtered out, the disease gene ranking performance improves substantially. However, the coverage drops from 3286 to 695 pairs. A) Disease gene rank histogram. B) Cumulative proportion of disease genes detected as the co-expression rank threshold is decreased from 1 to 0.