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Table 1 Characteristics of sample alignments.

From: An efficient visualization tool for the analysis of protein mutation matrices

Sequence Set

Reference sequence Characteristics

Derived sequences

Sample set (NCBI access code numbers)

Antibody (anti-TPO)

Low affinity antibody, usually a germline sequence

High-affinity germline derivatives directed against a single epitope

Reference sequence:

Z22191

Derivatives: AAD09370, AAD29291, AAD29292, AAD29293, P06888

Antibody (amyloidogenic vs. non-amyloidogenic)

Germline sequence

Set 1: Amyloid-forming derivatives of the germline sequence

 
  

Set 2: Non-amyloid-forming, high-affinity derivatives of the germline sequence

 

Hemagglutinin H5

Random hemagglutinin H5 sequence

All other available hemagglutinin H5 sequences

 

Olfactory receptors

Sequence that recognizes some functional group X

Sequences that recognize some functional group Y whose characteristics are diametrically opposed to the characteristics of X, or which are not related to the characteristics of X

Reference sequence:

NP_001011738.1 (short-chain alcohol-binding OR)

Derivatives (long-chain alcohol-binding ORs):

NP_064686.1

AAD27596.2

NP_038648.2

NP_667256.1

AAK00590.1