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Table 1 Results for rds01 using the Connectivity Map.

From: A simple and robust method for connecting small-molecule drugs using gene-expression signatures

rank ID compound score up down
1 1080 sirolimus 1 0.232 -0.578
2 913 colforsin 0.953 0.245 -0.527
3 1138 phentolamine 0.912 0.316 -0.423
4 1048 alpha-estradiol 0.886 0.324 -0.394
5 1115 phenanthridinone 0.869 0.379 -0.325
... ... ... ... ... ...
112 885 5186223 0.363 0.137 -0.157
113 3 metformin 0.342 0.158 -0.119
114 663 U0125 0 0.405 0.194
115 124 mesalazine 0 0.371 0.256
... ... ... ... ... ...
369 1008 geldanamycin 0 -0.43 -0.339
370 1064 17AAG 0 -0.436 -0.395
371 605 monastrol -0.38 -0.114 0.177
372 494 fluphenazine -0.392 -0.113 0.187
... ... ... ... ... ...
449 601 MK-886 -0.834 -0.303 0.336
450 604 arachidonic acid -0.855 -0.301 0.354
451 387 estradiol -0.901 -0.162 0.528
452 379 cobalt chloride -0.916 -0.238 0.464
453 378 tacrolimus -1 -0.23 0.536
  1. The connectivity scores of the random gene signature rds01 to the reference profiles in the Lamb Connectivity Map. The full tabulated results can be found in the supplementary data [see Additional file 1]. 113 reference profiles have positive connectivity scores, 83 reference profiles have negative connectivity scores.