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Table 1 Results for rds01 using the Connectivity Map.

From: A simple and robust method for connecting small-molecule drugs using gene-expression signatures

rank

ID

compound

score

up

down

1

1080

sirolimus

1

0.232

-0.578

2

913

colforsin

0.953

0.245

-0.527

3

1138

phentolamine

0.912

0.316

-0.423

4

1048

alpha-estradiol

0.886

0.324

-0.394

5

1115

phenanthridinone

0.869

0.379

-0.325

...

...

...

...

...

...

112

885

5186223

0.363

0.137

-0.157

113

3

metformin

0.342

0.158

-0.119

114

663

U0125

0

0.405

0.194

115

124

mesalazine

0

0.371

0.256

...

...

...

...

...

...

369

1008

geldanamycin

0

-0.43

-0.339

370

1064

17AAG

0

-0.436

-0.395

371

605

monastrol

-0.38

-0.114

0.177

372

494

fluphenazine

-0.392

-0.113

0.187

...

...

...

...

...

...

449

601

MK-886

-0.834

-0.303

0.336

450

604

arachidonic acid

-0.855

-0.301

0.354

451

387

estradiol

-0.901

-0.162

0.528

452

379

cobalt chloride

-0.916

-0.238

0.464

453

378

tacrolimus

-1

-0.23

0.536

  1. The connectivity scores of the random gene signature rds01 to the reference profiles in the Lamb Connectivity Map. The full tabulated results can be found in the supplementary data [see Additional file 1]. 113 reference profiles have positive connectivity scores, 83 reference profiles have negative connectivity scores.