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Figure 2 | BMC Bioinformatics

Figure 2

From: Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data

Figure 2

Difference of scores of mouse genes on first two PCs. The differentially expressed genes identified by Trinklein et al. [20] are marked '+'. These genes span mainly in the direction of the first PC. The first PC represents the pattern related to activation of genes. Genes on the positive side of the plane are up-regulated in wild-type and down-regulated in mutant mouse. Genes on the negative side of the plane are down-regulated in wild-type and up-regulated in mutant mouse. This indicates that Trinklein et al. [20] identified only the genes that are completely up- or down-regulated.

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BMC Bioinformatics

ISSN: 1471-2105

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