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Table 1 Estimated single-processor computing time on the SGI Altix XE 1300 Linux cluster system with 2.66 GHz Intel Clovertown processor, and the total number of tests for two-locus and three-locus analysis.

From: Parallel and serial computing tools for testing single-locus and epistatic SNP effects of quantitative traits in genome-wide association studies

Number of SNPs (N)

 

Two-locus analysis

Three-locus analysis

500,000

Computing time (T)

T ≈ 1.2 years

T ≈ 200,000 years

 

Number of tests (M)

M = (1.25) 1011

M = (2.08) 1016

1,000,000

Computing time (T)

T ≈ 5 years

T ≈ 1.5 million years

 

Number of tests (M)

M = (5.0) 1011

M = (1.67) 1017