Merging microsatellite data: enhanced methodology and software to combine genotype data for linkage and association analysis

Table 5 Results for ten markers aligned with the one-to-one format for three different priors on the number of theoretical alleles.

		# Bins		Default		Min.		Max.
Group	Locus	Ds1	Ds2	Pr(A1)	Dist.	Pr(A1)	Dist.	Pr(A1)	Dist.
a.)	D4S1531	8	8	0.962	0	0.987	0	0.975	0
	D4S1578	8	8	0.980	0	0.975	0	0.983	0
	D4S1591	6	6	0.997	0	0.989	0	0.993	0
b.)	D4S1534	10	11	0.601	0	0.849	0	0.491	0
	D4S2909	4	5	0.649	0	0.953	0	0.543	0
	D4S2966	6	7	0.665	0	0.884	0	0.579	0
c.)	D4S1637	7	8	0.353	3	0.431	0	0.395	3
	D4S2380	11	16	0.149	7	0.216	11	0.112	11
	D4S3042	13	16	0.304	10	0.326	12	0.220	8
d.)	D4S1517	9	11	0.593	0	0.926	12	0.557	0

Group a.) consists of markers where the top alignment contained n_min+ 1 theoretical alleles, the markers in b.) had a 2nd best alignment that had n_min+ 1 theoretical alleles, set c.) consists of markers with incorrect alignments, and d.) was an additional marker found to vary in alignment accuracy for different priors.

ISSN: 1471-2105