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Table 2 Haplotype estimation frequency error

From: NullHap – a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles

No

example description

error

  

Arlequin

PHASE

Haplo-IHP

NullHap

1

biallelic loci: A(A1, A2), B(B1, B2), C(C1, C2) no null variants

0%

0%

0%

0%

2

biallelic loci: A(A0, A1), B(B0,B1), C(C0, C1), null variants: A0, B0 and C0

61%

50%

1%

0%

3

multiallelic loci: A(A1, A2, A3), B(B1, B2, B3), no null variants

0%

1%

78%

0%

4

multiallelic loci: A(A0, A1, A2), B(B0,B1, B2), null variants: A0 and B0

62%

62%

100%

0%

5

multiallelic and biallelic loci with null variants: A(A0,A1,A2), B(B0,B1), C(C0,C1)

62%

48%

64%

0%

6

details in Table 2, A(A0,A1,A2), B(B1,B2,B3,B4), C(C0,C1)

79%

79%

82%

0%

  1. Haplotype estimation frequency error for six polymorphisms with varying locus characteristics.