Skip to main content
Figure 2 | BMC Bioinformatics

Figure 2

From: NITPICK: peak identification for mass spectrometry data

Figure 2

Efficient automated determination of the number of components in an area withoverlapping peaks using the BIC min (λ) termination criterion. The mean squared error MSE (scaled, dotted) decreases monotonically over the LARS steps and the generalized degrees of freedom GDF(λ) (dashed) increase monotonically. The resulting BIC(λ) measure(solid) exhibits a minimum BIC(λ 9 ) in the 9th LARS step and λ 9 is accepted as a minimizer because thelower bound BIC min 10 ) exceeds BIC(λ 9 ) in the 10th LARS step.

Back to article page