Table 5 Over-represented annotation terms and pathways in genes selected by t-test.
Functional Category | Term | efc | p-value |
|---|---|---|---|
UP_SEQ_FEATURE | cross-link:Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in & ubiquitin) | 6,320 | 0,000 |
GOTERM_MF_ALL | guanyl nucleotide binding | 2,344 | 0,000 |
GOTERM_MF_ALL | GTP binding | 2,256 | 0,001 |
INTERPRO_NAME | IPR000217:Tubulin | 6,384 | 0,001 |
INTERPRO_NAME | IPR002452:Alpha tubulin | 9,120 | 0,001 |
INTERPRO_NAME | IPR008280:Tubulin/FtsZ, C-terminal | 6,384 | 0,001 |
SP_PIR_KEYWORDS | Ubl conjugation | 7,089 | 0,001 |
INTERPRO_NAME | IPR000558:Histone H2B | 7,980 | 0,002 |
INTERPRO_NAME | IPR001660:Sterile alpha motif SAM | 4,966 | 0,002 |
GOTERM_CC_ALL | Chromatin | 2,683 | 0,003 |
SMART_NAME | SM00427:H2B | 7,422 | 0,003 |
INTERPRO_NAME | IPR000047:Helix-turn-helix motif, lambda-like repressor | 5,107 | 0,004 |
GOTERM_CC_ALL | Chromosome | 2,139 | 0,005 |
GOTERM_BP_ALL | protein metabolism | 1,243 | 0,005 |
SP_PIR_KEYWORDS | gtp-binding | 2,122 | 0,007 |
SP_PIR_KEYWORDS | dna-binding | 1,444 | 0,007 |
INTERPRO_NAME | IPR003008:Tubulin/FtsZ, GTPase | 5,804 | 0,008 |
SMART_NAME | SM00454:SAM | 4,453 | 0,008 |
PIR_SUPERFAMILY_NAME | SF002306:tubulin | 8,354 | 0,009 |
UP_SEQ_FEATURE | nucleotide phosphate-binding region:GTP | 2,107 | 0,013 |
KEGG_PATHWAY | HSA04540:GAP JUNCTION | 3,353 | 0,014 |
SP_PIR_KEYWORDS | chromosomal protein | 2,658 | 0,017 |
GOTERM_BP_ALL | microtubule-based movement | 3,257 | 0,017 |
GOTERM_BP_ALL | macromolecule metabolism | 1,154 | 0,019 |
GOTERM_BP_ALL | chromatin assembly or disassembly | 2,412 | 0,020 |
GOTERM_BP_ALL | cytoskeleton-dependent intracellular transport | 3,144 | 0,020 |
SP_PIR_KEYWORDS | DNA binding | 1,786 | 0,021 |
GOTERM_MF_ALL | GTPase activity | 2,252 | 0,021 |
UP_SEQ_FEATURE | DNA-binding region:Homeobox | 3,447 | 0,025 |
GOTERM_BP_ALL | protein polymerization | 3,398 | 0,027 |
UP_SEQ_FEATURE | domain:SAM | 5,618 | 0,028 |
INTERPRO_NAME | IPR007124:Histone-fold/TFIID-TAF/NF-Y | 2,883 | 0,030 |
GOTERM_MF_ALL | DNA binding | 1,272 | 0,034 |
GOTERM_BP_ALL | glycoprotein biosynthesis | 2,542 | 0,034 |
INTERPRO_NAME | IPR007125:Histone core | 3,192 | 0,035 |
GOTERM_BP_ALL | tRNA metabolism | 2,481 | 0,038 |
GOTERM_CC_ALL | nucleosome | 2,719 | 0,039 |
GOTERM_BP_ALL | nucleosome assembly | 2,682 | 0,041 |
GOTERM_CC_ALL | cell surface | 3,048 | 0,042 |
GOTERM_BP_ALL | cellular macromolecule metabolism | 1,176 | 0,043 |
UP_SEQ_FEATURE | domain:SH3 | 2,408 | 0,043 |
SP_PIR_KEYWORDS | nucleosome core | 2,999 | 0,044 |
GOTERM_BP_ALL | primary metabolism | 1,087 | 0,044 |
GOTERM_MF_ALL | binding | 1,060 | 0,045 |
GOTERM_MF_ALL | sequence-specific DNA binding | 1,739 | 0,046 |
GOTERM_BP_ALL | cellular protein metabolism | 1,173 | 0,049 |
UP_SEQ_FEATURE | repeat:Spectrin 5 | 7,584 | 0,053 |
UP_SEQ_FEATURE | repeat:Spectrin 6 | 7,584 | 0,053 |
UP_SEQ_FEATURE | repeat:Spectrin 7 | 7,584 | 0,053 |
UP_SEQ_FEATURE | repeat:Spectrin 8 | 7,584 | 0,053 |
UP_SEQ_FEATURE | repeat:Spectrin 9 | 7,584 | 0,053 |
GOTERM_CC_ALL | obsolete cellular component | 4,403 | 0,056 |
INTERPRO_NAME | IPR002017:Spectrin repeat | 2,483 | 0,058 |
GOTERM_BP_ALL | anion transport | 2,465 | 0,059 |
GOTERM_BP_ALL | metabolism | 1,070 | 0,062 |
GOTERM_MF_ALL | purine nucleotide binding | 1,255 | 0,062 |
GOTERM_BP_ALL | cellular metabolism | 1,073 | 0,068 |
GOTERM_MF_ALL | transcription factor activity | 1,398 | 0,068 |
GOTERM_MF_ALL | L-ascorbic acid binding | 6,552 | 0,071 |
GOTERM_BP_ALL | regulation of mitosis | 4,008 | 0,071 |
SP_PIR_KEYWORDS | vitamin c | 6,499 | 0,072 |
SMART_NAME | SM00177:ARF | 3,958 | 0,072 |
GOTERM_MF_ALL | carboxylic ester hydrolase activity | 2,621 | 0,073 |
GOTERM_BP_ALL | chromatin assembly | 2,338 | 0,073 |
INTERPRO_NAME | IPR006162:Phosphopantetheine attachment site | 6,384 | 0,074 |
INTERPRO_NAME | IPR006620:Prolyl 4-hydroxylase, alpha subunit | 6,384 | 0,074 |
GOTERM_CC_ALL | microtubule cytoskeleton | 1,816 | 0,076 |
GOTERM BP ALL | microtubule-based process | 2,127 | 0,077 |
GOTERM_MF_ALL | nucleotide binding | 1,206 | 0,083 |
SMART_NAME | SM00702:P4Hc | 5,938 | 0,084 |
GOTERM_MF_ALL | nucleic acid binding | 1,150 | 0,087 |
INTERPRO_NAME | IPR001715:Calponin-like actin-binding | 2,902 | 0,087 |
GOTERM_BP_ALL | biopolymer metabolism | 1,150 | 0,090 |
GOTERM_MF_ALL | enzyme regulator activity | 1,402 | 0,091 |
GOTERM_BP_ALL | glycoprotein metabolism | 2,043 | 0,091 |
SMART_NAME | SM00033:CH | 2,827 | 0,093 |
GOTERM_MF_ALL | enzyme activator activity | 1,737 | 0,097 |
INTERPRO_NAME | IPR001526:CD59 antigen | 5,472 | 0,098 |
INTERPRO_NAME | IPR005123:2OG-Fe(II) oxygenase | 5,472 | 0,098 |
INTERPRO_NAME | IPR006703:AIG1 | 5,472 | 0,098 |