From: Fregene: Simulation of realistic sequence-level data in populations and ascertained samples
General parameters (only applies to populations A and B) | |
---|---|
Chromosome Length | 20 Mb |
# Generations | 200, 000 |
# Sequences | 21, 000 |
Per-site mutation rate | 2.3 × 10-8 |
Recombination model | |
Per site crossover rate: | 1.1 × 10-8 |
Per site Gene conversion rate: | 4.5 × 10-9 |
Proportion of recombination events occurring in hotspots | 80% |
Hotspot length: | 2.0 kb |
Gene conversion length: | 0.5 kb |
Mean distance between hotspots: | 8.5 kb |
Selection parameters (if applicable) | |
Prop. of sites under selection: | 5 × 10-4 |
Proportion of selected sites locally under selection: | 0.5 |
Mean # generations before selected sites are switched off | 50, 000 |
selection coefficient: | s ~ 0.1 × (0.005, 0.052) + 0.9 × (-0.01, 0.0052) |
dominance coefficient: | h ~ 0.8 × (0.5, 0.2) + 0.3 × (1.2, 0.22) |