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Table 1 Biochemical reactions that make up our bacterial gene expression model (version incorporating the host's genome).

From: Increasing the efficiency of bacterial transcription simulations: When to exclude the genome without loss of accuracy

Left

Right

Forward Rate constant

Backward rate constant

operon_ns + Rpoly

closed_Rpoly_prom_ns

k_on_Rpoly_prom_ns/(v/1000)

k_off_Rpoly

closed_Rpoly_prom_ns

open_Rpoly_prom_ns

k_isomerization

 

open_Rpoly_prom_ns

operon_ns + Rpoly_operon_ns_1

k_prom_clearance

 

Rpoly_operon_ns_1

Rpoly_operon_ns_2 + mRNA

k_transcription_ns

 

Rpoly_operon_ns_2

Rpoly_operon_ns_3 + mRNA

k_transcription_ns

 

Rpoly_operon_ns_3

Rpoly_operon_ns_4 + mRNA

k_transcription_ns

 

Rpoly_operon_ns_4

Rpoly_operon_ns_5 + mRNA

k_transcription_ns

 

Rpoly_operon_ns_5

Rpoly_operon_ns_6 + mRNA

k_transcription_ns

 

Rpoly_operon_ns_6

Rpoly_operon_ns_7 + mRNA

k_transcription_ns

 

Rpoly_operon_ns_7

Rpoly + mRNA_small

k_transcription_ns/0. 871794871794871

 

operon_s + Rpoly

closed_Rpoly_prom_s

k_on_Rpoly_prom_s/(v/1000)

k_off_Rpoly

closed_Rpoly_prom_s

open_Rpoly_prom_s

k_isomerization

 

open_Rpoly_prom_s

operon_s + Rpoly_operon_s

k_prom_clearance

 

Rpoly_operon_s

Rpoly + stable_RNA

k_transcription_s

 

V

2v

k_cell_div

 
 

operon_ns

k_rep_operon_ns

 
 

operon_s

k_rep_operon_s

 
 

Rpoly

k_rep_Rpoly

 

plas + Rpoly

closed_Rpoly_prom_reporter

k_on_Rpoly_prom_reporter/(v/1000)

k_off_Rpoly

closed_Rpoly_prom_reporter

open_Rpoly_prom_reporter

k_isomerization

 

open_Rpoly_prom_reporter

plas + Rpoly_reporter + incom_mRNA_reporter

k_prom_clearance

 

Rpoly_reporter

Rpoly + mRNA_reporter

k_transcription_reporter

 

incom_mRNA_reporter

 

k_transcription_reporter

 

mRNA_reporter

 

k_deg_mRNA_reporter

 

incom_mRNA_reporter

 

k_deg_mRNA_reporter

 

Rpoly_reporter

Rpoly

incom_mRNA_reporter*k_deg_mRNA_reporter/Rpoly_reporter

 
  1. Gene expression model incorporating the host's genome. Lists of the biochemical reactions that make up our bacterial gene expression model, for the version of the model that includes an "averaged" version of the host cell's genome. Columns Left and Right represent the left and right sides of chemical reactions, and the Forward and Backward rate constants are associated with the forward and reverse reactions.