Table 4 Comparison of the number of known complexes matched by the predicted clusters (consisting of 3 or more proteins) generated by IPCA and DPClus.
From: Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
Overlapping Score(OS) | IPCA(T in = 0.9;SP ≤ 2) | DPClus(Ov;CP in = 0.5;D in = 0.9) |
|---|---|---|
OS ≥ 0.1 | 134 (202) | 116 (191) |
OS ≥ 0.2 | 103 (165) | 78 (128) |
OS ≥ 0.3 | 87 (116) | 63 (85) |
OS ≥ 0.4 | 75 (104) | 54 (74) |
OS ≥ 0.5 | 56 (83) | 35 (52) |
OS ≥ 0.6 | 45 (67) | 28 (41) |
OS ≥ 0.7 | 27 (42) | 15 (25) |
OS ≥ 0.8 | 21 (36) | 10 (20) |
OS ≥ 0.9 | 14 (29) | 5 (15) |
OS = 1.0 | 13 (28) | 5 (15) |