Table 3 Top10 genes selected by the proposed multi-scale ICA method on yeast cell cycle data
From: Knowledge-guided multi-scale independent component analysis for biomarker identification
Rank | ORF | Name | Short Description |
|---|---|---|---|
1 | YPL256C | CLN2 | CycLiN; G1 cyclin involved in regulation of the cell cycle |
2 | YOL007C | CSI2 | Chitin Synthesis Involved; protein of unknown function |
3 | YKR013W | PRY2 | Pathogen Related in Yeast; protein of unknown function |
4 | YDL003W | MCD1 | Mitotic Chromosome Determinant; expression is cell cycle regulated and peaks in S phase |
5 | YML027W | YOX1 | Homeodomain-containing transcriptional repressor |
6 | YBR088C | POL30 | POLymerase; proliferating cell nuclear antigen (PCNA) |
7 | YLR183C | TOS4 | Target of SBF; promoters of some genes involved in pheromone response and cell cycle; |
8 | YIL140W | AXL2 | AXiaL budding pattern; glycosylated by Pmt4p; potential Cdc28p substrate |
9 | YGR189C | CRH1 | Congo Red Hypersensitive; cell wall protein; putative chitin transglycosidase |
10 | YER070W | RNR1 | RiboNucleotide Reductase; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits |