Table 1 Binding modes within each Interacting Superfamily Group (ISG)

interacting superfamilies

number of complexes^a

this work

Keskin

overcounts^b

c.67.1 c.67.1

71(65)

12

13

1

d.174.1 d.174.1

47(34)

2

2

1

c.37.1 c.37.1

41(32)

20

17

0^c

b.1.1 b.1.1

39(18)

14

8

1

c.1.1 c.1.1

38

3

3

0

d.117.1 d.117.1

36

1

1

0

c.76.1 c.76.1

32(31)

2

1

0

c.2.1 c.2.1

26(25)

9

8

0

c.71.1 c.71.1

25(24)

6

5

0

d.169.1 d.169.1

21

5

5

0

b.60.1 b.60.1

21(19)

10

9

1

b.29.1 b.29.1

20(17)

7

9

0

e.3.1 e.3.1

18(13)

6

7

0

c.69.1 c.69.1

18(12)

14

10

0

d.17.4 d.17.4

17(11)

4

4

0

d.5.1 d.5.1

16

8

8

0

d.144.1 d.144.1

16(11)

12

7

0

c.68.1 c.68.1

16(12)

5

4

0

a.39.1 a.39.1

16(14)

7

6

0

e.7.1 e.7.1

15

2

2

0

a.133.1 a.133.1

15(12)

10

7

2

b.47.1 g.3.11

17

1

1

0

a.118.6 a.102.4

15(7)

1

1

0

b.47.1 b.47.1

13(11)

12

9

1

c.61.1 c.61.1

12

5

5

0

d.92.1 d.92.1

11

5

5

0

d.32.1 d.32.1

11(9)

3

3

0

c.94.1 c.94.1

11(7)

4

4

0

c.1.10 c.1.10

11(9)

5

4

0

c.52.1 c.52.1

10

6

5

1

d.1.1 d.1.1

9(5)

3

2

0

c.47.1 c.47.1

9(4)

6

4

0

a.1.1 a.1.1

9(8)

4

3

0

d.9.1 d.9.1

8(6)

3

3

0

b.6.1 b.6.1

8

1

1

0

a.123.1 a.123.1

8(4)

3

2

1

c.26.1 c.26.1

5(3)

4

3

0

c.66.1 c.66.1

4(2)

3

2

0

d.2.1 d.2.1

4

3

3

0

c.1.8 c.1.8

4

2

2

0

Total

743(621)

206

195

9