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Table 1 Normalisation methods used in the comparison. Normalisation methods used in the comparison. Offset and scaling parameters are used as in Equation 1. Note that for each method these parameters are estimated globally as well as locally and evaluated separately. Formal definitions of these methods can be found in Additional file 2.

From: Comparison of normalisation methods for surface-enhanced laser desorption and ionisation (SELDI) time-of-flight (TOF) mass spectrometry data

No

Offset (Θ)

Scaling (Δ)

Working name

Citation

1

0

mean

Zero mean

[15,16]

2

0

median

Zero median

[8]

3

0

sd

Zero SD

 

4

0

mad

Zero MAD

 

5

mean

sd

Mean SD

 

6

median

mad

Median MAD

 

7

median

iqr

Median quantile

[17]

8

min

range

Min range

([18])