Figure 4

Horizontal vs Vertical. Header HILs: similar to both schemata. Cell HILs: While in horizontal HILs the fields have clear meanings (FS, SS, CD5 etc), vertical HILs are useless because field labels cannot be resolved. Measurement HILs: In the horizontal case, cell fields maintain their clear meanings and HIL gains value from the additional fields of the Header segment. In the vertical case, the additional information of the Header segment can be used to resolve the cell field labels. Even though both HILs contain the same amount of information, it remains hidden in the vertical case. Experiment HILs: Horizontal HILs manage to remain simple (all fields have clear meanings and data is perfectly aligned among different records) despite the fact that the amount of information has significantly grown. For vertical HILs to become useful, the user must resolve field labels, unify the different naming forms of the same antigen and finally align all the fragmented values of the same antigen under a single field.