Figure 1
From: Stability of the core domain of p53: insights from computer simulations
Structure of the Core domain. A. The structure of the p53 core domain in dimeric form complexed with DNA, taken from the crystal structure with RCSB code 2AHI [21]). Highlighted in magenta is the DNA binding helix H2, in red is the dimeric interface, blue is loop L1, yellow is loop L3. Zinc ion is represented as grey spheres; B. The two core residues Tyr236 and Thr253 shown in stick, surrounded in spheres by the predominantly hydrophobic core residues.