Figure 10
From: Stability of the core domain of p53: insights from computer simulations
The core region of wtp53 and dp53. A. The residues in the core region of p53 (the left panel) and dp53 (the right panel) showing the differences in orientation of Ile251 and Ile255 when the Thr253 is mutated to Ile253 and Tyr236 is mutated to Phe236; B. The residues in the neighbourhood of the rotating ring that differ between p53 (Val, Met), p63 (Ala, Leu) and p73 (Gly, Leu).