Figure 2

Sequence alignment. A. Multiple sequence alignment of the residues of the core domains of p53, p63, p73. Highlighted in red are the residues that have been mutated in this study and in blue are the Tyr residues whose mobilities have been examined. B. Superposition of the structures of the core domains of p53, p63 and p73 used in this study. Drawn in sticks are the residues that have been mutated in this study: Tyr236, Thr253.