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Table 2 The workflow of window size selection and parameter optimization.

From: Predicting RNA-binding sites of proteins using support vector machines and evolutionary information

 

Sliding window size (w)

C and γ

Smoothing window size (ws)

Weight parameter (w1 and w-1)

Step 1

3 ≤ w ≤ 41 (step = 2)

Default

-

Default ratio

Step 2

Optimized w from step 1

-3 ≤ log2C ≤ 12 (step = 1)

 

Default ratio

  

-3 ≤ log2γ ≤ -15 (step = -1)

  

Step 3

Optimized w from step 1

Optimized C and γ from step 2

3 ≤ ws ≤ 11 (step = 2)

Default ratio

Step 4

Optimized w from step 1

Optimized C and γ from step 2

Optimized ws from step 3

1 ≤ w1 ≤ 8# (step = 1), w-1 = 1

Final

Optimized w from step 1

Optimized C and γ from step 2

Optimized ws from step 3

Optimized w1 and w-1 from step4

  1. # In the RBP107 data set, we test w1 ranged from 1 to 10 (step = 1).