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Table 1 SVM performance during testing (labeled with the keyword 'Max') and comparison with SIFT predictions.

From: Exhaustive prediction of disease susceptibility to coding base changes in the human genome

  HGMD dbSNP     
  TP FN TN FP Sensitivity Specificity Accuracy F-measure
  Testing set created using random mutations not used for training
SVM Complete ; Max 16527 3567 64378 12454 82.2 83.8 83.5 67.4
SVM Conservation Only ; Max 14467 5627 49178 27659 72.0 64.0 65.7 46.5
  Testing set created to allow comparison with SIFT
SIFT 159 245 13995 5281 39.4 72.6 71.9 5.4
SVM Complete 287 117 12049 7227 71.0 62.5 62.7 7.2
SVM Conservation Only 230 174 10216 9060 56.9 53.0 53.1 4.7
  1. Abbreviations: TP = True Positives; FP False Positives; TN = True Negatives; FN = False Negatives.