Figure 6

ROC curve and false discovery rates (FDR) for phenotypic similarities between diseases provided by PhenUMA and PhenomeNET. A: ROC curves for phenotypic similarities between OMIM diseases. For all the cases we used the same reference dataset. This dataset are all inferred OMIM disease pairs that are those diseases associated with the same gene/s. It is noteworthy that the results from Robinson and Resnik are equivalent to those in Additional file 1: Figure S1A and S1B, respectively, B: FDR for increasing values of phenotypic similarity scores.