Figure 6
From: Efficient prediction of human protein-protein interactions at a global scale
Schematic diagram of breast cancer pathway. BRCA1 plays a central role in breast cancer by connecting DNA damage and chromatin remodeling to downstream processes such as cell cycle progression and DNA repair. Black lines (edges) represent biochemical pathways, red and green edges are novel and known PPIs, respectively. Ovals and clouds represent proteins and protein complexes, respectively. Red ovals represent novel proteins that are associated with breast cancer pathway on the basis of the predicted interactions they form.