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Table 6 Enrichment of biological process for proteins with highest Hub Degree (Hubs) or Betweeness Centrality (B.C.) measurements (Top 10, Top 25, and Top 50)

From: Efficient prediction of human protein-protein interactions at a global scale

  Biological process Top 10 Top 25 Top 50
# prot P-value # prot P-value # prot P-value
Hubs Transcription regulation 7 2.26E-06 16 3.15E-10 28 1.93E-14
Regulation of gene expression 7 4.88E-06 16 1.69E-09 29 2.82E-14
B.C. Protein kinase activity 2 5.99E-02 6 1.01E-07 20 8.61E-18
Regulation of cell death 3 3.96E-05 11 7.60E-09 19 1.82E-12
Signaling 4 5.49E-05 13 5.90E-09 33 7.45E-12