Table 6 Enrichment of biological process for proteins with highest Hub Degree (Hubs) or Betweeness Centrality (B.C.) measurements (Top 10, Top 25, and Top 50)
From: Efficient prediction of human protein-protein interactions at a global scale
| Â | Biological process | Top 10 | Top 25 | Top 50 | |||
|---|---|---|---|---|---|---|---|
# prot | P-value | # prot | P-value | # prot | P-value | ||
Hubs | Transcription regulation | 7 | 2.26E-06 | 16 | 3.15E-10 | 28 | 1.93E-14 |
Regulation of gene expression | 7 | 4.88E-06 | 16 | 1.69E-09 | 29 | 2.82E-14 | |
B.C. | Protein kinase activity | 2 | 5.99E-02 | 6 | 1.01E-07 | 20 | 8.61E-18 |
Regulation of cell death | 3 | 3.96E-05 | 11 | 7.60E-09 | 19 | 1.82E-12 | |
Signaling | 4 | 5.49E-05 | 13 | 5.90E-09 | 33 | 7.45E-12 | |