Skip to main content
Figure 1 | BMC Bioinformatics

Figure 1

From: Mammalian transcriptional hotspots are enriched for tissue specific enhancers near cell type specific highly expressed genes and are predicted to act as transcriptional activator hubs

Figure 1

Combinatorial binding events overlap across multiple cell types. A. schematic diagram of a genomic region with genome tracks of six ChIP sequencing samples in a cell type marking singletons (bound by only one transcription-related factor), combinatorials (bound by few transcription-related factors) and hotspots (peaks bound by more than five transcription-related factors). B. A table listing all 10 cell types used along with the number of transcription factors C. bar graph of fraction of peaks in hotspots across 10 cell types. D. Heatmap of Pearson’s correlation coefficients of peaks in 30 sets (three groups of 10 cell types) with a hierarchical clustering tree showing that combinatorials clustered according to the groups. E. box plots for peak heights for the three groups (singletons – red, combinatorials - green, hotspots - blue) for T cells and macrophages.

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us