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Table 3 Summary of all detected groups of genes from Model 2 on yeast data

From: Fast and robust group-wise eQTL mapping using sparse graphical models

a Group ID b SNPs set size c gene set size d GO category
1 63 294 oxidation-reduction process
2 78 153 thiamine biosynthetic process
3 94 871 rRNA processing
4 64 204 nucleosome assembly
5 70 288 ATP synthesis coupled proton transport
6 43 151 branched chain family amino acid biosynthetic...
7 76 479 mitochondrial translation
8 47 349 transmembrane transport
9 64 253 cytoplasmic translation
10 72 415 response to stress
11 64 225 mitochondrial translation
12 62 301 oxidation-reduction process
13 83 661 oxidation-reduction process
14 69 326 cytoplasmic translation
15 71 216 oxidation-reduction process
16 66 364 methionine metabolic process
17 74 243 cellular amino acid biosynthetic process
18 63 224 transmembrane transport
19 23 50 de novo’ pyrimidine base biosynthetic process
20 66 205 cellular amino acid biosynthetic process
21 81 372 oxidation-reduction process
22 33 126 oxidation-reduction process
23 81 288 pheromone-dependent signal transduction...
24 53 190 pheromone-dependent signal transduction...
25 91 572 oxidation-reduction process
26 66 46 cellular cell wall organization
27 111 1091 translation
28 89 362 cellular amino acid biosynthetic process
29 62 217 transmembrane transport
30 71 151 cellular aldehyde metabolic process
  1. aGroup ID corresponding to Figure 12. bNumber of SNPs in the group. cNumber of genes in the group. dThe most significant GO category enriched in the associated gene set. The enrichment test was performed using DAVID [29]. The gene function is defined by GO category. Adjusted p-values are reported by using permutation test. Adjusted p-values are indicated by , where 10−210−3, 10−310−5, 10−510−10.