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Table 3 Summary of all detected groups of genes from Model 2 on yeast data

From: Fast and robust group-wise eQTL mapping using sparse graphical models

a Group ID

b SNPs set size

c gene set size

d GO category

1

63

294

oxidation-reduction process ∗

2

78

153

thiamine biosynthetic process ∗

3

94

871

rRNA processing ∗∗∗

4

64

204

nucleosome assembly ∗∗

5

70

288

ATP synthesis coupled proton transport ∗∗∗

6

43

151

branched chain family amino acid biosynthetic... ∗∗

7

76

479

mitochondrial translation ∗∗∗

8

47

349

transmembrane transport ∗∗

9

64

253

cytoplasmic translation ∗∗∗

10

72

415

response to stress ∗∗

11

64

225

mitochondrial translation ∗

12

62

301

oxidation-reduction process ∗∗

13

83

661

oxidation-reduction process ∗

14

69

326

cytoplasmic translation ∗

15

71

216

oxidation-reduction process ∗

16

66

364

methionine metabolic process ∗

17

74

243

cellular amino acid biosynthetic process ∗∗∗

18

63

224

transmembrane transport ∗∗

19

23

50

de novo’ pyrimidine base biosynthetic process ∗

20

66

205

cellular amino acid biosynthetic process ∗∗∗

21

81

372

oxidation-reduction process ∗∗

22

33

126

oxidation-reduction process ∗∗∗

23

81

288

pheromone-dependent signal transduction... ∗∗

24

53

190

pheromone-dependent signal transduction... ∗∗

25

91

572

oxidation-reduction process ∗∗∗

26

66

46

cellular cell wall organization ∗

27

111

1091

translation ∗∗∗

28

89

362

cellular amino acid biosynthetic process ∗∗

29

62

217

transmembrane transport ∗∗

30

71

151

cellular aldehyde metabolic process ∗∗

  1. aGroup ID corresponding to Figure 12. bNumber of SNPs in the group. cNumber of genes in the group. dThe most significant GO category enriched in the associated gene set. The enrichment test was performed using DAVID [29]. The gene function is defined by GO category. Adjusted p-values are reported by using permutation test. Adjusted p-values are indicated by ∗, where ∗10−2∼10−3, ∗∗10−3∼10−5, ∗∗∗10−5∼10−10.