Figure 1
From: Sensitive and highly resolved identification of RNA-protein interaction sites in PAR-CLIP data
Graphical representation of the Bayesian network employed to discriminate PAR-CLIP-specific from extrinsic transitions. The data generating process is modeled hierarchically, where i) Θ encodes the unobserved source of the transition (PAR-CLIP-specific or -independent), ii) X represents the relative substitution frequency and iii) Y is the number of observed transitions at the position, which exhibits a coverage of z reads.