Table 6 The length differences of CpG islands between normal and mutant isolates in HBV Genotypes A-G
From: Mutations and CpG islands among hepatitis B virus genotypes in Europe
Genotype | CpG island I | CpG island II | CpG island III | CpG island IV | CpG island V | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Location (bp) | Length (bp) | LD and PD | Location (bp) | Length (bp) | LD and PD | Location (bp) | Length (bp) | LD and PD | Location (bp) | Length (bp) | LD and PD | Location (bp) | Length (bp) | LD and PD | |
A (n = 123) Normal | 78-285 | 208 | 8 (3.85%) | 1113-1676 | 564 | 128 (22.7%) | 2185-2466 | 282 | 14 (4.96%) | 529-632 | 104 | 1 (0.96%) | - | - | - |
A (n = 27) Mutant | 76-291 | 216 | 1228-1663 | 436 | 2196-2463 | 268 | 530-632 | 103 | - | - | |||||
B (n = 6) Normal | 108-287 | 180 | - | 1139-1683 | 545 | - | 2298-2462 | 165 | - | - | - | - | - | - | - |
B (n = 0) Mutant | - | - | - | - | - | - | - | - | - | - | |||||
C (n = 1) Normal | 186-286 | 101 | - | 1219-1663 | 445 | - | 2280-2442 | 263 | - | - | - | - | - | - | - |
C (n = 0) Mutant | - | - | - | - | - | - | - | - | - | - | |||||
D (n = 106) Normal | 185-286 | 102 | 254 (249%) | 1100-1674 | 575 | 128 (22.3%) | 2265-2443 | 179 | 99 (55.31%) | 454-555 | 102 | 45 (44.12%) | - | - | - |
D (n = 93) Mutant | 77-432 | 356 | 1191-1637 | 447 | 2188-2465 | 278 | 443-589 | 147 | - | - | |||||
E (n = 12) Normal | 72-286 | 215 | - | 1212-1674 | 463 | 24 (5.2%) | 2172-2456 | 285 | 175 (61.4%) | 471-583 | 113 | - | - | - | - |
E (n = 2) Mutant | - | - | 1230-1668 | 439 | 2334-2443 | 110 | - | - | - | - | |||||
F (n = 2) Normal | - | - | - | 1216-1673 | 458 | - | 2298-2458 | 161 | - | - | - | - | 1921-2038 | 118 | - |
F (n = 0) Mutant | - | - | - | - | - | - | - | - | - | - | |||||
G (n = 6) Normal | - | - | - | 1160-1628 | 469 | 3 (0.64%) | 2304-2497 | 194 | 46 (23.71%) | - | - | - | - | - | - |
G (n = 5) Mutant | - | - | 1163-1628 | 466 | 2350-2497 | 148 | - | - | - | - | |||||