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Table 6 The length differences of CpG islands between normal and mutant isolates in HBV Genotypes A-G

From: Mutations and CpG islands among hepatitis B virus genotypes in Europe

Genotype CpG island I CpG island II CpG island III CpG island IV CpG island V
Location (bp) Length (bp) LD and PD Location (bp) Length (bp) LD and PD Location (bp) Length (bp) LD and PD Location (bp) Length (bp) LD and PD Location (bp) Length (bp) LD and PD
A (n = 123) Normal 78-285 208 8 (3.85%) 1113-1676 564 128 (22.7%) 2185-2466 282 14 (4.96%) 529-632 104 1 (0.96%) - - -
A (n = 27) Mutant 76-291 216 1228-1663 436 2196-2463 268 530-632 103 - -
B (n = 6) Normal 108-287 180 - 1139-1683 545 - 2298-2462 165 - - - - - - -
B (n = 0) Mutant - - - - - - - - - -
C (n = 1) Normal 186-286 101 - 1219-1663 445 - 2280-2442 263 - - - - - - -
C (n = 0) Mutant - - - - - - - - - -
D (n = 106) Normal 185-286 102 254 (249%) 1100-1674 575 128 (22.3%) 2265-2443 179 99 (55.31%) 454-555 102 45 (44.12%) - - -
D (n = 93) Mutant 77-432 356 1191-1637 447 2188-2465 278 443-589 147 - -
E (n = 12) Normal 72-286 215 - 1212-1674 463 24 (5.2%) 2172-2456 285 175 (61.4%) 471-583 113 - - - -
E (n = 2) Mutant - - 1230-1668 439 2334-2443 110 - - - -
F (n = 2) Normal - - - 1216-1673 458 - 2298-2458 161 - - - - 1921-2038 118 -
F (n = 0) Mutant - - - - - - - - - -
G (n = 6) Normal - - - 1160-1628 469 3 (0.64%) 2304-2497 194 46 (23.71%) - - - - - -
G (n = 5) Mutant - - 1163-1628 466 2350-2497 148 - - - -
  1. LD: the length difference of CpG islands between the normal and mutant isolates; PD: the percent difference in normal CpG length (LD/CpG length of normal isolate x 100%).