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Table 4 Power simulation: power vs. selected nominal levels for all strategies

From: Novel genetic matching methods for handling population stratification in genome-wide association studies

    Power 1− β
Test Units Validation α =0 . 01 α =0 . 001 α =0 . 0001
CAT AT 0.665 0.450 0.271
CAT RSU Pairs Cluster 0.881 0.782 0.662
CAT RSU Pairs Vicinity 0.846 0.710 0.558
CAT RSU Groups Cluster 0.809 0.705 0.594
CAT RSU Groups Vicinity 0.833 0.729 0.607
CAT RSU Clusters 0.808 0.704 0.597
MCAT(2) RSU Pairs Cluster 0.884 0.783 0.658
MCAT(2) RSU Pairs Vicinity 0.823 0.705 0.549
MCAT(2) RSU Groups Cluster 0.907 0.808 0.685
MCAT(2) RSU Groups Vicinity 0.872 0.745 0.591
MCAT(2) RSU Clusters 0.894 0.782 0.641
MCAT(1) AT Pairs Cluster 0.862 0.733 0.579
MCAT(1) AT Pairs Vicinity 0.813 0.641 0.454
MCAT(1) AT Groups Cluster 0.903 0.797 0.671
MCAT(1) AT Groups Vicinity 0.878 0.751 0.603
MCAT(1) AT Clusters 0.898 0.786 0.650
LRmds LRT 7 PCs 0.871 0.741 0.588
LRmds LRT 14 PCs 0.908 0.805 0.678
LRmds LRT 28 PCs 0.901 0.798 0.664
  1. 11,010 SNPs, 1845 individuals, nominal error level α and power 1−β. 10,000 independent SNPs were used to obtain structure information. The abbreviations in the second column are: AT asymptotic test, RSU resampling simulation within units (99,995 cycles), LRT likelihood ratio test. Column N shows the number of individuals included and in brackets the number of pairs p, groups g and clusters c.