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Figure 2 | BMC Bioinformatics

Figure 2

From: EGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib

Figure 2

Comparison between local changes of the predicted structures and WT EGFR. (A -F) display an example of insertion, deletion, duplication, modification and substitution (single-point and double-point), corresponding to V769_CV_D770, delE746_S752, dulN771_H773, delT751_I759insN, L165Q and S72IV78M, respectively. The dark gray chains represent the WT structures while the magenta chains stand for the predicted ones with Rosetta.

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BMC Bioinformatics

ISSN: 1471-2105

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