EGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib

Table 1 The naming rules of EGFR mutations

Name	Representation	Example	Description
Insertion	Ap_I_Bq	V769_ASV_D770	Residues insertion
Deletion	delAp_Bq	delE746_S752	Residues deletion
Duplication	dulAp_Bq	dulA767_V769	Residues duplication
Modification	delAp_BqinsI	delE746_A750insAP	Combination of residues deletion and insertion
Substitution	ApB	T790M	Single-point mutation
Substitution	ApC_BqD	E709A_G719A	Double-point mutation

ISSN: 1471-2105