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Table 1 The naming rules of EGFR mutations

From: EGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib

Name Representation Example Description
Insertion Ap_I_Bq V769_ASV_D770 Residues insertion
Deletion delAp_Bq delE746_S752 Residues deletion
Duplication dulAp_Bq dulA767_V769 Residues duplication
Modification delAp_BqinsI delE746_A750insAP Combination of residues deletion and insertion
Substitution ApB T790M Single-point mutation
ApC_BqD E709A_G719A Double-point mutation