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Table 2 Distribution of EGFR mutations

From: EGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib

Name

Number of mutations

Number of patients

Percentage of all mutation types

Percentage of all the patients

Insertion

7

9

6.25%

0.96%

Deletion

6

285

5.36%

30.25%

Duplication

6

18

5.36%

1.91%

Modification

24

120

21.42%

12.74%

Substitution

69

510

61.61%

54.14%