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Table 2 Distribution of EGFR mutations

From: EGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib

Name Number of mutations Number of patients Percentage of all mutation types Percentage of all the patients
Insertion 7 9 6.25% 0.96%
Deletion 6 285 5.36% 30.25%
Duplication 6 18 5.36% 1.91%
Modification 24 120 21.42% 12.74%
Substitution 69 510 61.61% 54.14%