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Table 1 Data sets analyzed

From: Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective

 

GEO accession

Platf

Ref

Description

n

Covariate model

Ref. Blood

GSE39981

27K

[18,52]

Human leukocyte subtypes purified from whole blood samples.

73

[whole|gran|mono|B|NK|CD4 + T|CD8 + T|Pan-T]

GSE35069

450K

[47]

Human leukocyte subtypes purified from whole blood samples.

54

[whole|neut|eos|gran|mono|B|NK|CD4 + T|CD8 + T]

Blood

GSE30229*

27K

[16]

Peripheral blood from 92 head and neck squamous cell carcinoma (HNSCC) patients and 92 controls.

184

[control|HNSCC] + age

GSE19711

27K

[1]

Whole blood from 131 ovarian cancer cases (drawn pre-treatment) and 274 controls.

405

[control|ov Cancer] + age

GSE42861

450K

[17]

Peripheral blood from 354 rheumatoid arthritis patients and 335 controls.

689

[control|arthritis]

Breast Tum

GSE32393

27K

[35]

Breast tumor samples: 91 invasive ductal, 13 invasive lobular, 10 mucinous or medullary; 76 were ER+.

114

[ER-|ER+] + [duct|lob|muc or med] + age

Gastric

GSE30601

27K

[53]

203 gastric tumors and 94 matched gastric non-malignant samples.

297

[normal|tumor]

Liver

GSE60753

450K

[54]

34 normal liver tissues, 21 cirrhotic tissues (due to alcoholism), 45 cirrhotic tissues [due to chronic hepatitis B (HBV) or C (HCV) viral infection].

100

[normal|CirrEtOH|CirrV]

Artery

GSE46394

450K

[55]

15 normal aortic tissues, 15 atherosclerotic lesions, 19 carotid atherosclerotic samples.

49

[normal|ath|carotid ath] + [female|male] + age

  1. * For the HNSCC data, age is not available in the GEO submission GSE30229, but was obtained from the authors of the original study.