Figure 8

Per residue free energy decomposition of the residues at the interface of the EGFR kinase and MIG-6_s1 complex. The van der Waals energy (red line), the sum of the coulombic interactions and the polar part of the solvation free energy (light blue) and the total binding free energy (black dot) for key residues with the values ≤ − 1.0 kcal/mol. All values were given in kcal/mol. Gray line represented the cut off of-1.0 kcal/mol.